Compound found in octopus ink could lead to new cancer treatments
A recent study by Hernández-Zazueta et al. aimed to chemically synthesise and evaluate the anti-proliferative (suppress cell growth) and anti-inflammatory potential of ozopromide (OPC), a novel compound recently isolated from the ink of the Common Octopus Octopus vulgaris.
Results from the research suggest that OPC has the potential to alleviate inflammation and to successfully impact cell viability, inducing both early and late apoptosis or cell death. The compound should be further studied for anticancer activity as it could potentially lead to the development of new cancer treatments.
Many marine-derived food products such as octopus ink contain bioactive compounds that exhibit potential human health benefits.
Hernández-Zazueta, M. S., García-Romo, J. S., Luzardo-Ocampo, I., Carbonell-Barrachina, Á. A., Taboada-Antelo, P., Rosas-Burgos, E. C., Ezquerra-Brauer, J. M., Martínez-Soto, J. M., Del Carmen Candia-Plata, M., Del Carmen Santacruz-Ortega, H., & Burgos-Hernández, A. (2023). N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers. Food and Chemical Toxicology, 177, 113829. DOI: https://doi.org/10.1016/j.fct.2023.113829.